Regorafenib Tablets are multi kinase inhibiting drugs that are formulated for treatment of certain types of cancers. They get metabolized in liver with help of UGT1A9 enzyme with bioavailability range of 69 to 83%. These tablets are known to have ability to inhibit VEGFR2-TIE2. Active compound used in formulation of Regorafenib Tablets has chemical formula C21H17ClF4N4O4 with molar mass of 482.82 g/mol. They are admired for having targeted mode of action against angiogenic and oncogenic RTKs.
Excellent protein binding ability of 99.5%
Has elimination life of 20 to 30 hours
Excreted in feces & urine