Kryxana Tablet has been specifically formulated for treatment of certain kinds of breast cancers. It contains ribociclib as main chemical having molecular formula C23H30N8O and molar mass of 434.55 g/mol. upon ingestion, this tablet gets absorbed in gut and within 4 hours its highest levels can be seen in blood plasma. Kryxana Tablet works by inhibiting cyclin dependent kinases 4 & 6 that are responsible for cell multiplication and division of tumor cells.
Metabolism takes place in liver with help of CYP3A4 enzyme
Has protein binding ability of around 70%
Can be used in combination with ALK or MEK inhibitors