Iressa Gefitinib Tablets are prescribed during cancer treatment of lung & breast and is also known to be effective for other types of tumors. They are EGFR inhibitors that interrupt signals by tumor cells required for cell growth. These tablets have gefitinib as active compound with molecular formula C22H24ClFN4O3 and molar mass of 446.902 g/mol. Iressa Gefitinib Tablets have elimination half life of 6 to 49 hours, which depends on concentration of dose and get excreted in feces.
Metabolized mainly by CYP3A4 enzyme
Have good protein binding ability of 90%
Binds to ATP binding site of EGFR